A Brief Snapshot of the Situation: Cervical Cancer in
Latin America and the Caribbean, 2001

It has been estimated that 470,606 incident cases and 233,372 deaths due to malignant neoplasm of the cervix uteri will have occurred among women globally in the year 2000 (Globocan 2000, IARC). Over 80% of this estimated burden will have occurred in less developed countries, where cervical cancer is the leading cause of malignancy among women. Further, during the year 2000, it has also been estimated that 77,291 cases and 30,570 deaths due to this malignant neoplasm will have occurred among women in Latin America and the Caribbean, accounting for roughly 17% and 13.6% of total cancer cases and deaths (excluding skin cancers) in this region, respectively.

At the turn of the twenty first century, cervical cancer remains a significant public health problem in Latin America and the Caribbean. A review of age standardized incidence and mortality rates reveals that as a region, it is surpassed on these epidemiological indices only by East Africa and Melanesia (Table 1).

Table 1

Malignant Neoplasm of the Cervix Uteri
Age Standardized Incidence and Mortality Rates per 100 000 Population
By Regions – 2000

Region

Incidence Rate

Mortality Rate

Eastern Africa

Middle Africa

Northern Africa

Southern Africa

Western Africa

Caribbean

Central America

South America

North America

Eastern Asia

S. Eastern Asia

S. Central Asia

Western Asia

Eastern Europe

North. Europe

South. Europe

Western Europe

Australia

Melanesia

Micronesia

Polynesia

44.32

25.08

16.77

30.32

20.28

35.78

40.28

30.92

7.88

6.44

18.26

26.47

4.77

16.81

9.84

10.18

10.43

7.72

43.81

12.31

28.98

24.24

14.16

9.08

16.45

10.87

16.84

17.03

11.97

3.23

3.19

9.65

14.95

2.50

6.20

4.00

3.25

3.74

2.66

23.78

6.16

15.20

Source: Globocan 2000. International Agency for Research on Cancer

Of grave concern is the fact that while significant declines in both incidence and mortality measures have occurred in Canada, the United States of America and other established market economies over the last forty years, similar trends have not been observed in most countries of Latin America and the Caribbean. For example, cancer registries in Costa Rica, Colombia, Peru and Brazil, have persistently recorded high annual age-standardized incidence rates, in excess of 20.0 cases per 100 000 females, over the period 1978 to 1992. By comparison, the rates for Canada and the United States of America (Table 2) have been less than 10.0 cases per 100 000 females.

Table 2

Malignant Neoplasm of the Cervix Uteri
Average Annual Age Standardized Incidence Rates per 100 000 Population
Selected Countries of the Americas
1978-1992

Country

1978-1982

1983-1987

1988-1992

Brazil [Goiania]

48.9

37.1

Canada

10.5

10.2

7.8

Colombia [Cali]

48.2

42.2

34.4

Costa Rica

36.9

26.1

24.5

Martinique

29.3

24.3

Peru [Trujillo]

54.6

53.5

Puerto Rico

15.6

11.5

9.8

Source: Cancer Incidence in Five Continents. Volumes V, VI, VII. Edited by Parkin et al.

 

The mortality data reflects a similar situation, in which few countries of Latin America and the Caribbean have demonstrated significant declines in reported mortality over the period 1968 through 1993 as compared with the North American profile (Robles et al: 1996) (Figure 1).

 

Figure 1

Although cervical cancer incidence and mortality rates increase with increasing age, the greatest disease burden is borne by women in their middle years. A review of reported cervical cancer mortality data from countries in Latin America and the Caribbean indicates that women in the age group, 35 through 54 years, repeatedly account for the greatest proportion of annual deaths. (PAHO’s SHA Technical Information System, 1988-1995).

Estimated age-specific mortality data for the year 2000 demonstrate that in the Region of the Americas, the highest rates are observed in Central America and the Caribbean, followed by South America [Figure 2: Globocan 2000, IARC].

 

Figure 2