“Every clinical trial must be registered in a publicly accessible database before recruitment of the first subject”. Declaration of Helsinki,
Clinical Trial Registration is one of the most critical sources of scientific evidence on the safety and effectiveness of health interventions. It enhances transparency and public trust in the conduct of clinical research, and gives visibility to new research so that it can be considered in reviews of the scientific literature. The registration of all interventional trials is considered to be a scientific, ethical and moral responsibility.
- To minimize known risks and potential harm form unnecessary exposures.
- To accelerate research and improve collaboration among researchers.
- To identify and discourage selective (biased) reporting of research and unnecessary duplication of research.
- To provide a means of comparing the originally approved ethics protocols with the actual studies carried out.
Tendencies in the Number of Trials and Recruiting Trials in the Americas - 2005 to 2010Source: www.who.int/ictrp
Clinical Trials Documents,