What’s the Issue: Methylmercury Exposure
Exposure to mercury affects the immune system, alters genetic and enzyme systems, and damages the nervous system, including coordination and the senses of touch, taste, and sight (1). Methylmercury is the most toxic form of mercury. People are exposed to methylmercury almost entirely by eating contaminated fish that are at the top of aquatic foodchains (2)
Research to Practice: Ecosystem Research to Characterize Methylmercury Exposure Routes in the Amazon
Regional increases of mercury levels in fish were generally thought to be directly attributable to mercury releases from local gold mining operations. However, an extensive three year study, conducted from 1994-1997 along the Tapajós River basin, shed new light on the question (3). These studies demonstrated that mercury from mining operations contributed only a small percentage of the total mercury found in the river (4).
As with any of the chemical elements, mercury exists naturally as part of the Earth and over time, the ultimate sink for mercury is in the sediments of the Earth's oceans and lakes (5). The scientists linked high mercury concentrations with the initiation of slash-and-burn agriculture, a common practice in the Amazon today. By removing trees, loggers and 'slash and burn' farmers unearth naturally occurring mercury deposits bound to soil particles and rains wash this mercury rich soil into nearby water ways where it is converted to methyl mercury (a form easily taken up by fish and humans).
Researchers established a close relationship with the community to educate community members about the risks of eating different fish species through posters depicting methylmercury concentrations in different types of fish. Local residents also began to change agricultural techniques. In a joint initiative with researchers, small farmers identified the crops that could improve diets and reduce the intake of mercury (6). The researchers also worked with local fishermen to identify the stretches of river that would have lower methylmercury levels and be safest for fishing.
These interventions based on scientific evidence and carried out in collaboration with the local community have produced concrete results: from 1995 to now, measured mercury levels in local residents dropped significantly (7)
What’s Next? Further Research on Ecosystem Health and its links to Human Health
Further research that examines the links between ecosystem and human health is vital to understand environmental determinants of human diseases. The rapid economic development and urbanization of countries in the Latin American and Caribbean region are exacerbating a whole host of emerging and re-emerging environmental health threats. The World Health Organization estimates that worldwide, 13 million deaths could be prevented every year by making our environments healthier (8).
For more information on environmental health visit the PAHO Sustainable Development and Environmental Health Website
(1) Edna M Yokoo, Joaquim G Valente, Lynn Grattan, Sérgio Luís Schmidt, Illeane Platt and Ellen K Silbergeld. 2003. Low level methylmercury exposure affects neuropsychological function in adults.Environmental Health: A Global Access Science Source 2:8.
(2) USGS Factsheet.
(3) IDRC Research Program Case Studies.
(4) René Canuel, Marc Lucotte and Sylvie Boucher de Grosbois. 2009. Mercury cycling and human health concerns in remote ecosystems in the Americas. S.A.P.I.EN.S, 2.1. Link.
(5) Wheeler, M. 1996. Measuring Mercury. Environmental Health Perspectives 104:8. Link.
(6) Lebel, J. 2005. Salud: um enfoque ecosistémico. Bogotá: Alfaomega.
(8)WHO Environmental Health:http://www.who.int/features/factfiles/environmental_health/en/index.html
Funding Opportunity Announcement for Cancer Research in the Caribbean
Application deadline 1 December 2014. , Scientific Review, Final Decision and disbursement of funds: January 31, 2015. See detailed information here.
KBR presents at 22nd Cochrane Colloquium held in Hyederabad, India. 21-26 September 2014
TDR: Grants and funding opportunities
TDR, the Special Programme for Research and Training in Tropical Diseases, has issued an invitation for letters of interest regarding the topic: Improving the careers of women research scientists in infectious diseases of poverty. This invitation is intended to address the strategies and techniques that can be used to improve the career opportunities of female researchers from low- and middle-income countries. Applications should be submitted by the 30th of September 2014. More information about the call for this invitation, and others, can be found here.
Who We Are
Why Invest in Research for Health?
A series of case studies examining the benefits of investment in research for health.
Framework & Mandates
Policy on Research for Health (abridged)
The 49th Directing Council approved PAHO’s Regional Policy on Research for Health which offers a strategic approach to strengthen research governance and knowledge translation.
Art for Research
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To read about internship opportunities in research at different PAHO entities, read testimonials from former interns, or apply, visit our internship section.