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CHA.HIV. Drug Resistance

HIV Drug Resistance (HIVDR) is defined as the ability of HIV to mutate and reproduce in the presence of antiretroviral drugs. Drug resistance may develop in patients on antiretroviral therapy (acquired or secondary drug resistance), or may be transmitted from a person with acquired resistance to an individual without previous exposure to antiretrovirals (primary or transmitted drug resistance). The development and transmission of drug resistance are a serious concern for the efficacy of antiretroviral treatment from both clinical and public health perspective.

PAHO supports the planning and implementation of national HIVDR prevention and assessment strategies in the region, based on the World Health Organization global HIVDR strategy and integrated into national HIV surveillance and monitoring and evaluation programs. More information on the WHO HIVDR strategy can be found at:

Last Updated on Tuesday, 14 May 2013 09:44


HIVDR Early Warning Indicators (2010) (WHO)

World Health Organization HIV Drug Resistance Laboratory Guidance (2010) (WHO)

*World Health Organization/HIVResNet Drug Resistance Laboratory Strategy

*World Health Organization surveys to monitor HIV drug resistance prevention and associated factors in sentinel antiretroviral treatment sites

*Recommendations for surveillance of transmitted HIV drug resistance in countries scaling up antiretroviral treatment

*World Health Organization's global strategy for prevention and assessment of HIV drug resistance




(*) These articles were made freely available by International Medical Press

Last Updated on Tuesday, 14 May 2013 09:44


Links of Interest

WHO HIV Drug Resistance Homepage

WHO HIV Drug Resistance Publications

WHO HIVDR Prevention and Assessment Strategy Homepage

WHO HIV ResNet - Global HIV Drug Resistance Network

WHO HIV Drug Resistance Laboratory Network

Institute for Drug Resistance

Stanford Drug Resistance Database

Rega Institute Database and Drug Resistance Algorithm

French National Agency for AIDS Research Drug Resistance Algorithm

Brazilian HIV Drug Resistance Algorithm


CROI 2011 - 18th Conference on Retroviruses and Opportunistic Infections

Last Updated on Tuesday, 14 May 2013 09:45

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