Vaccines and immunization

Immunization is a global health and development success story, saving millions of lives every year. Vaccines reduce risks of getting a disease by working with your body’s natural defences to build protection. When you get a vaccine, your immune system responds.

We now have vaccines to prevent more than 20 life-threatening diseases, helping people of all ages live longer, healthier lives. Immunization currently prevents 3.5-5 million deaths every year from diseases like diphtheria, tetanus, pertussis, influenza and measles.

Immunization is a key component of primary health care and an indisputable human right. It’s also one of the best health investments money can buy. Vaccines are also critical to the prevention and control of infectious disease outbreaks. They underpin global health security and will be a vital tool in the battle against antimicrobial resistance.

The Covid-19 pandemic, associated disruptions, and Covid-19 vaccination efforts strained health systems in 2020 and 2021, resulting in dramatic setbacks. However, from a global perspective recovery is on the horizon -  in 2022 diphtheria-pertussis-tetanus (DTP) immunization coverage, albeit unevenly between countries, has almost recovered to 2019 levels.

Measles, because of its high transmissibility, acts as a “canary in the coalmine”, quickly exposing any immunity gaps in the population. Still, 22 million children missed their routine first dose of measles vaccine in 2022, compared to 19 million in 2019.

Vaccines train your immune system to create antibodies, just as it does when it’s exposed to a disease. However, because vaccines contain only killed or weakened forms of germs like viruses or bacteria, they do not cause the disease or put you at risk of its complications.

Vaccines protect against many different diseases, including:

cervical cancer cholera COVID-19 diphtheria hepatitis B influenza Japanese encephalitis malaria measles meningitis mumps pertussis

pneumonia polio rabies rotavirus rubella tetanus typhoid varicella yellow fever

Some other vaccines are currently being piloted, including those that protect against Ebola or malaria, but are not yet widely available globally.

Not all these vaccinations may be needed in your country. Some may only be given prior to travel, in areas of risk, or to people in high-risk occupations. Talk to your healthcare worker to find out what vaccinations are needed for you and your family.

WHO is working with countries and partners to improve global vaccination coverage, including through these initiatives adopted by the World Health Assembly in August 2020.

Immunization Agenda 2030

IA2030 sets an ambitious, overarching global vision and strategy for vaccines and immunization for the decade 2021–2030. It was co-created with thousands of contributions from countries and organizations around the world. It draws on lessons from the past decade and acknowledges continuing and new challenges posed by infectious diseases (e.g. Ebola, COVID-19).

The strategy has been designed to respond to the interests of every country and intends to inspire and align the activities of community, national, regional and global stakeholders towards achieving a world where everyone, everywhere fully benefits from vaccines for good health and well-being. IA2030 is operationalized through regional and national strategies and a mechanism to ensure ownership and accountability and a monitoring and evaluation framework to guide country implementation.

• Immunization Agenda 2030: A Global Strategy to Leave No One Behind
• Implementing the Immunization Agenda 2030: A Framework for Action