Cholera is an acute diarrheal infection caused by ingestion of food or water contaminated with the bacterium Vibrio cholerae. It has a short incubation period, ranging from two hours to five days.
The bacterium produces an enterotoxin that causes a copious, painless, watery diarrhea that can quickly lead to severe dehydration and death if treatment is not promptly given. Vomiting also occurs in most patients.
Cholera affects both children and adults and can kill within hours. Person-to-person transmission is not common.
Among people who develop symptoms, about 80-90% of episodes are of mild or moderate severity and are difficult to distinguish clinically from other types of acute diarrhea. Less than 20% of ill persons develop acute watery diarrhea with moderate or severe dehydration.
People with low immunity, such as malnourished children or people living with HIV, are at greater risk of death if infected.
Cholera remains a public health threat in the Americas and is one of the key indicators of social development. While the disease no longer poses a threat to countries with minimum standards of hygiene, it remains a challenge to countries where access to safe drinking water and adequate sanitation cannot be guaranteed.
For this reason, a multidisciplinary approach based on prevention, preparedness and response, along with an efficient surveillance system, is key to mitigating cholera outbreaks, controlling cholera in endemic areas and reducing deaths.
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