This guide seeks to orient implementation of Zika virus disease surveillance. It is based on the experience acquired in the current epidemic in the Region of the Americas. The document provides a general, though not exhaustive, guide to surveillance activities. Each country will need to adapt it to its own capacities, epidemiological situation, and health system. The guide also includes a brief clinical description of the disease, its neurological manifestations, and congenital Zika virus syndrome, based on available information, with a view to correctly reporting suspected cases. Case definitions and laboratory detection and diagnosis procedures are proposed.
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