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“Every research study involving human subjects must be registered in a publicly accessible database before recruitment of the first subject” Declaration of Helsinki, World Medical Association.

An important proportion of clinical trials that have been completed are never published or their results are partially reported.

The World Health Organization regards trial registration as the publication of an internationally-agreed set of information about the design, conduct and administration of clinical trials. These details are published on a publicly-accessible website managed by a registry conforming to WHO standards.

“Clinical trial registration is now an essential part of the scientific process and is assumed to reduce bias in health literature, promote higher levels of research accountability, address selective reporting, and make trial data accessible for completed and ongoing trials.’’ ¹ It enhances transparency and public trust in the conduct of clinical research, and gives visibility to new research so that it can be considered in reviews of the scientific literature.

Within the Knowledge Management, Bioethics and Research Department, the Knowledge Translation program provides technical cooperation to facilitate the implementation of the trial registration initiative in the Americas as well as regional support to the WHO International Clinical Trials Registry Platform (ICTRP)

Main features of the program:

ICTRP Trial Registration in the Americas

Search for trials Reporting findings

Trial Registration initiative over time

Last Updated on Wednesday, 16 July 2014 18:00

Contact us: in PAHO/HQ:; in the countries: list of focal points

Regional Office for the Americas of the World Health Organization
525 Twenty-third Street, N.W., Washington, D.C. 20037, United States of America
Tel.: +1 (202) 974-3000 Fax: +1 (202) 974-3663

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