| AA-HA! | Global Accelerated Action for the Health of Adolescents Framework |
| AIDS | Acquired immunodeficiency syndrome |
| APR | A Promise Renewed |
| ASRH | Adolescent sexual and reproductive health |
| BMI | Body mass index |
| CARICOM | Caribbean Community |
| CDC | Centers for Disease Control and Prevention |
| CICAD | Inter-American Drug Abuse Control Commission |
| CLADEM | Latin American and Caribbean Committee for the Defense of Women’s Rights |
| CLAP | Latin American Center for Perinatology, Women and Reproductive Health |
| COMISCA | Consejo de Ministros de Salud de Centroamérica [Council of Ministers of Health of Central America] |
| CRC | Committee on the Rights of the Child |
| CSE | Comprehensive sexuality education |
| DAL | Disability-adjusted life year |
| DHS | Demographic and Health Surveys |
| DMFT | Decayed, missing, and filled teeth (index) |
| DPaT | Diphtheria, pertussis, and tetanus vaccine |
| ECLAC | Economic Commission for Latin America and the Caribbean |
| EWEC | Every Woman Every Child |
| FGL | Family, Gender and Life Course Department (PAHO) |
| FCTC | Framework Convention on Tobacco Control |
| GBD | Global Burden of Disease |
| GSHS | Global School-based Student Health Survey |
| GYTS | Global Youth Tobacco Survey |
| HED | Heavy episodic drinking |
| HIV | Human immunodeficiency virus |
| HPV | Human papillomavirus |
| IDB | Inter-American Development Bank |
| IHME | Institute for Health Metrics and Evaluation |
| ILO | International Labour Organization |
| IMAN | Integrated Management of Adolescent Needs |
| IPPF | International Planned Parenthood Federation |
| LAC | Latin America and the Caribbean |
| LGB | Lesbian, gay, and bisexual |
| LGBT | Lesbian, gay, bisexual, and transgender |
| MICS | Multiple Indicator Cluster Surveys |
| MSM | Men who have sex with men |
| NCD | Noncommunicable disease |
| NEET | Not in education, employment, or training |
| NGO | Nongovernmental organization |
| OAS | Organization of American States |
| OCTs | Overseas Caribbean territories |
| OID | Inter-American Observatory on Drugs |
| ORAS - CONHU | Organismo Andino de Salud - Convenio Hipólito Unanue [Andean Health System - Hipólito Unanue Convention] |
| PAHO | Pan American Health Organization |
| SDGs | Sustainable Development Goals |
| SDH | Social determinant of health |
| SES | Socioeconomic status |
| SGBV | Sexual and gender-based violence |
| SIA | Sistema Informático del Adolescente [Adolescent Information System] |
| SRH | Sexual and reproductive health |
| SRHR | Sexual and reproductive health and rights |
| STI | Sexually transmitted infection |
| Td | Tetanus and diphtheria vaccine |
| UN | United Nations |
| UNESCO | United Nations Education, Scientific and Cultural Organization |
| UNFPA | United Nations Population Fund |
| UNICEF | United Nations Children’s Fund |
| UNODC | United Nations Office on Drugs and Crime |
| YLD | Years of life lost due to disability |
| YLL | Years of life lost due to premature mortality |
| YRBS | Youth Risk Behavior Survey |
| WHO | World Health Organization |