Evaluation of commercially available anti-dengue virus immunoglobulin M tests; 2009 (PDF)

The arthropod-borne flavivirus dengue virus (DENV) is found mostly in tropical and subtropical regions. Four distinct serotypes (DENV 1-4) cocirculate in many of the dengue-endemic regions of the world. Approximately 2.5 billion people live in areas at risk for acquiring dengue. Of an estimated 50 million infections annually, around 500 000 cases (of which a high proportion are children) are hospitalized with dengue haemorrhagic fever (DHF), a more severe form of the disease.