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It has been estimated that between 140,000 to 400,000 new cases of acute hepatitis B occur annually in the Americas. Two thirds of them are believed to occur in South America, primarily in areas within the Amazon Basin.


Recommendations:

  • Routine vaccination of all children living in the Amazon Basin is recommended as well as in other areas, if any, with high endemicity (HbsAg prevalence equal or greater than 7%).
  • Routine vaccination is also recommended for those at high risk of infection, such as Elath care workers and hospital staff.
  • Because HBV infection is largely asymptomatic among young children, disease surveillance has a limited role in monitoring the hepatitis B vaccination program. Instead, the vaccination program must be monitored through mechanism of process indicators (e.g., proportion of children or workers vaccinated) and through studies of asymptomatic hepatitis B virus infection (i.e. serologic studies).