Situation Report: Mpox Multi-Country Outbreak - Region of the Americas - 3 September 2025 - PAHO/WHO

Download	Between 2022 and 31 July 2025, a total of 158,425 confirmed cases of mpox have been reported globally, from 127 countries and territories. The Region of the Americas (44.1%) contributes the largest proportion of cases, followed by the African (31.4%) and European (19.3%) Regions. In the Region of the Americas, a cumulative total of 69,905 confirmed cases of mpox, including 153 deaths, were reported in 31 countries and territories between 2022 and 2025. This document provides highlights of the epidemiological situation in the Region of the Americas and the PAHO/WHO response.