To support countries in their efforts to strengthen detection of TB infection, disease and drug resistance, the WHO Global TB Programme issues evidence-based policy guidance on TB testing strategies and technologies; this guidance is routinely updated. Since the most recent consolidated guidelines on TB diagnosis were issued in 2024: - new evidence has become available on the use of WHO-recommended rapid diagnostic tests (WRDs) for the initial detection of TB and resistance to rifampicin among populations that are at increased risk of TB-related morbidity and mortality (e.g. people living with HIV andchildren);
- a systematic assessment of evidence on molecular WRDs (mWRDs) previously recommended as individual products was completed to determine the placement of mWRDs within existing or new classes of TB diagnostic technologies; and
- a call from countries was received to combine the policy guidance on TB infection, disease and drug-resistance testing into these consolidated
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