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Suicide is determined by the interaction between psychosocial, biological and psychiatric factors. In the Americas, 65,000 people die from suicide every year. 90% of suicidal victims have a diagnosable mental disorder. The age-adjusted suicide rate, per 100,000 population, is 7.3 (11.5 for men and 3.0 for women) and it accounts for 1.6% of total disability-adjusted life years (DALYs). Suicide is the third leading cause of death in the group aged 20 to 24 years, and fourth in the groups aged 10 to 19 and 25 to 44. The population aged >70 years has the highest rate (12.4 per 100,000 population). Suicide attempts are 10-20 times more common than completed suicide and while suicidal ideation is a predictor of suicidal acts, the strongest risk factor is a previous suicide attempt. The most commonly used methods are suffocation, firearms, and poisoning (using pesticides, in particular). In Latin America and the Caribbean, the age-adjusted rate is 5.2 (8.4 in men and 2.1 in women). Mortality from suicide continues to be higher in men than in women (male-female ratio of 3.8); however, women report more suicide attempts.

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