Immunization in the Americas: 2025 Summary

As part of its technical assistance to the countries and territories of the Region of the Americas, the Pan American Health Organization (PAHO) disseminates official information highlighting the progress achieved and the challenges faced within the Region. To this end, PAHO periodically publishes various technical documents related to immunization, most notably the annual booklet *Immunization in the Americas*. This document summarizes immunization coverage across the Region of the Americas and illustrates the work carried out by immunization programs throughout the year. The publication includes tables featuring demographic, morbidity, program management, financing, and socioeconomic data for the Region, as well as reported immunization coverage and surveillance indicators, among other data points. With PAHO’s support, the countries of the Americas have made remarkable strides in providing a protective umbrella against vaccine-preventable diseases for their populations. Sustained high levels of national immunization coverage, the eradication of polio, the interruption of endemic measles virus transmission, and efforts toward the elimination of rubella and congenital rubella syndrome stand as hemispheric benchmarks of this progress. Currently—thanks to the Region’s immunization programs—target populations are being vaccinated across the entire life course. Examples include influenza vaccination for at-risk adult populations; vaccination of adolescents and adults (both men and women) to achieve rubella elimination; and HPV vaccination aimed at reducing the burden of cervical cancer morbidity. Disseminating this information makes it possible to identify key aspects that highlight the progress and challenges facing the Region’s immunization programs, with the ultimate goal of fostering continuous improvement and ensuring that vaccination reaches every corner of the Americas, leaving no one behind.