The Global Vaccine Action Plan (GVAP) 2011-2020 was developed with a vision of having a world in which all individuals and communities enjoy lives free from vaccine-preventable diseases. Significant progress has been made towards the GVAP goals in the African region. The Africa Regional Strategic Plan for Immunization 2014-2020 (RSPI) which is aligned with the GVAP goals is the main guiding strategic plan for immunization in the African region. The RSPI aims at achieving universal immunisation coverage and reducing mortality and morbidity from vaccine preventable diseases (VPD) by the end of 2020. In January 2017, Heads of State from across Africa signed the Addis Declaration on Immunization (ADI) and committed to ensuring that everyone in Africa, no matter who they are or where they live, can access equitably all the required vaccines. The ADI is recognised as a political and advocacy instrument which is being used to support the implementation of the RSPI at the highest level of government.