What’s in this technical brief?
This technical update by the World Health Organization (WHO) aims to:
- update the dosing considerations for oral pre-exposure prophylaxis (PrEP) containing TDF for men who have sex with men;
- summarize current evidence on the safety and efficacy of event-driven PrEP (ED-PrEP);
- describe the rationale for offering ED-PrEP as an alternative to daily oral PrEP to men who have sex with men as part of comprehensive HIV prevention and sexual health services;
- discuss considerations for offering ED PrEP to men who have sex with men, including clear messaging on how men who have sex with men can switch from ED-PrEP to daily dosing (and vice-versa).