Measles and Rubella Elimination Regional Monitoring and Re-Verification Commission
The Regional Verification Commission (RVC), an independent body of public health experts appointed by the Pan American Health Organization (PAHO), is responsible for monitoring the verification and re-verification of the elimination of measles, rubella, and congenital rubella syndrome (CRS) in countries across the Americas. Additionally, the RVC advices PAHO’s Director regarding general and specific recommendations and status changes for any country or the entire region.
Established in 2019, the RVC succeeded the International Commission of Experts, which had verified the elimination of rubella and CRS in 2015 and measles in 2016. The RVC continues this work in the post-elimination era, ensuring that countries maintain the necessary public health standards to prevent the re-establishment of endemic transmission of these diseases.
How does a country become verified as Measles or Rubella Free?
To be verified as measles-free, a country must provide comprehensive evidence to the RVC demonstrating:
- High vaccination coverage, both through routine immunization and targeted campaigns.
- Interruption of endemic transmission for at least 12 consecutive months, confirmed by epidemiological and laboratory data.
- Robust surveillance systems capable of detecting and investigating suspected cases quickly, supported by molecular epidemiology (e.g., genotyping).
- Effective outbreak response, including rapid deployment of trained teams and implementation of selective or mass vaccination strategies, considering the epidemiologic situation.
- Submission of detailed documentation to the RVC, including surveillance quality assessments, outbreak investigation results, and immunization data.
The RVC reviews this evidence in collaboration with each country’s National Commission for the Sustainability of Elimination and sends a formal report to the Director of PAHO, who assess it and formally communicates the decision publicly and to the respective country.
What happens if a country loses its measles or rubella free status?
Losing measles elimination status means that endemic transmission has been re-established, often due to gaps in vaccination, surveillance, or outbreak response. While there are no formal penalties, the consequences can be serious:
- Increased risk of measles or rubella outbreaks, especially among vulnerable populations.
- Greater pressure on national health systems.
- Reversal of public health gains.
To regain elimination status, the country must:
- Interrupt endemic transmission for at least 12 months.
- Submit a corrective action plan to PAHO, aligned with the regional framework.
- Strengthen immunization, surveillance, and outbreak response systems.
For example, after reestablishing endemic measles transmission in 2019, Brazil successfully interrupted endemic transmission by mid-2022 and regained its measles-free status in 2024.
How is a country re-verified after an outbreak?
Re-verification follows the same rigorous process as initial verification. The country must:
- Demonstrate 12 months without endemic transmission.
- Strengthen the vaccination program, surveillance performance, and outbreak response, providing comprehensive data reports on the progress achieved.
- Work with its National Sustainability Commission to compile and submit evidence to the RVC.
The RVC then reviews the submission and determines whether elimination status can be reinstated.
Historical Timeline: Measles-Free Verification in the Americas
- In 1994, the countries in the region adopted the resolution to eliminate measles. Last endemic case of the pre-elimination period was reported in Venezuela in 2002.
- In 2003, the countries in the region adopted the resolution to eliminate rubella and congenital rubella syndrome (CRS). Last endemic cases of rubella and CRS in the pre-elimination period were reported in 2009 in Argentina and Brazil, respectively.
- In 2015, the Region of the Americas became the first to achieve endemic rubella and CRS elimination.
- In 2016, the Americas Region officially achieved measles elimination after being declared free of endemic measles. To date, it is the only region in the world to have achieved this milestone. However, sustaining this achievement requires a significant effort from every country in the region, given the high transmissibility of the disease.
- In 2018, Venezuela lost its measles elimination status due to a prolonged outbreak that began in 2017. After interrupting the outbreak and maintaining no endemic transmission for approximately four years, it was reverified as free of measles in 2023.
- In 2019, Brazil lost its measles elimination status. Following extensive vaccination, surveillance, and rapid response efforts, the country was reverified as measles-free in November 2024. Brazil maintained interruption of endemic transmission for more than two years before the country declared again as measles free, as the last endemic case was identified in June 2022. In total, approximately five years elapsed between the loss and reinstatement of measles-free status.
- In 2024, the region was reverified as free of endemic measles thanks to the coordinated efforts of all member countries to improve epidemiological surveillance, rapid response, and vaccination against the disease.
- In October 2024, Canada reported the start of a new measles outbreak in New Brunswick. Since then, the outbreak has spread to multiple provinces including Manitoba, Ontario, Quebec, Alberta, British Columbia, and Saskatchewan. There are over 5,000 confirmed cases reported nationwide as of mid-October and is considered still active.
- In January 2025, the US reported the start of a measles outbreak that is also considered still active, with over 1,600 confirmed cases as of mid-October.
- In February 2025, Mexico reported the start of an ongoing measles outbreak, with over 4,000 confirmed cases as of the same date.
Members of the commission
- Jon Andrus (United States-Chair)
- Angela Gentile (Argentina)
- Fernando de la Hoz (Colombia)
- Herminio Hernández (Perú)
- José Ignacio Santos (México)
- Marilda Siqueira (Brazil)
- Susan Reef (United States)
- Tracy Evans-Gilbert (Jamaica)
- More information: https://iris.paho.org/handle/10665.2/55074
