Cryptococcosis in People with HIV

Cryptococcosis in People with HIV
 Cryptococcosis in People with HIV


Cryptococcosis is a disease that imposes a significant burden on HIV patients in Latin America and the Caribbean, with a prevalence of approximately 10% in individuals with advanced disease and a high mortality rate of between 15% and 25%. It is estimated that about 5300 cases occur in the region per year.

Diagnostic delays and limited access to fungicidal medications (such as 5-fluocytosine) are associated with poorer outcomes, such as increased mortality or increased risk of sequelae. Updated WHO guidelines suggest point-of-care screening in patients with CD4 counts of less than 200 cells/mL, active management of intracranial pressure, and therapeutic regimens based on liposomal amphotericin, 5-fluocytosine, and high-dose fluconazole.

This webinar will discuss current treatment recommendations and the management of special situations and be convened by PAHO.


Wednesday, 29 May 2024


11:00am-01:00pm, EST Time

Original language


11:00-11:10 am       Welcome remarks
Dr. Omar Sued, PAHO

11:10-11:30 am       Cryptococcosis in people with HIV: Strategies in the public health sector in Brazil
Dr. Ronaldo Hallal. National HIV and STI Directorate, Brazil

11:30-11:50 am       What's New in the Clinical Management of Cryptococcosis
Dr. Joe Jarvis. Department of Clinical Research. Faculty of Infectious and Tropical Diseases. London School of Hygiene and Tropical Medicine (LSHTM)

11:50-12:10 pm      When to start ART in people with cryptococcosis and management of systemic inflammatory response syndrome: A systematic review
Dr. Jose M. Miro, Senior Consultant, Infectious Diseases, Hospital Clinic of Barcelona, Spain. Professor of Medicine, University of Barcelona, Spain. IDIBAPS/CIBERINFEC investigator. FESCMID/FIDSA

12:10-12:15 pm      Presentation of clinical cases Ecuador
Moderator: Dra. Maria G. Yerovi

12:15-12:30 pm      Clinical case 1: Cryptococcal meningitis
Dr. Jesus Dawaher. 
Pablo Arturo Suárez General Hospital, Ministry of Public Health of Ecuador, Quito-Ecuador

12:30-12:45 pm      Clinical case 2: Cryptococcal disease
Dr. Marcos Molina
José Carrasco Arteaga Specialty Hospital, Social Security, Cuenca-Ecuador

12:45-12:55 pm      Questions and Answers

12:55-13:00 pm       Closure
Dr. Omar Sued, PAHO