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Bioethics

Bioethics is the discipline that examines the ethical issues arising in different areas of health, including public health, health care, and health research. Its purpose is to guide health decision-making through rigorous ethical analysis that makes ethical criteria explicit. In the Region of the Americas, PAHO promotes the systematic integration of ethics analysis in all areas of work in health.

  • Public health, the delivery of health care, and health research present us with numerous ethical challenges.
  • Emergencies and novel technologies enhance the demand for ethical guidance. 
  • Bioethics is the discipline that seeks to elucidate the ethical problems that arise in relation to health.
  • Bioethics examines what ought to be done in health-related situations, beyond what is legally required.
  • It provides ethical frameworks for public health decision-making, which are necessary to prioritize resources, especially in contexts of scarcity.
  • Integrating ethics in health decisions strengthens transparency and trust.

Through its Regional Bioethics Program, PAHO supports Member States in integrating ethics into all health-related activities. The Program promotes a demand-driven, translational bioethics approach, with a focus on research ethics and public health ethics.

With the goal of ensuring health research is always conducted ethically, PAHO works closely with Member States strengthening research ethics systems and advancing ethical research that meets the needs of the people in the Americas. With the goal of systematically integrating ethics in public health, PAHO builds capacity to include ethical deliberations in decision-making processes and to assess the value judgments that are embedded in health policies and public health interventions. 

PAHO ’s actions include the development of technical guidance, the strengthening of institutional capacities, the promotion of regional networks, and the development of practical tools to advance ethics review of research and ethical deliberation for public health decision-making.

Videos on research ethics

When does health research need ethics review?  

What do Research Ethics Committees review?

Courses
Curso Etica de la Salud  Publica
 REGIONAL COURSE: “Ética de la salud pública

Developed by the Regional Program on Bioethics and the PAHO Virtual Campus for Public Health (VCPH), this free, self-paced course on “Public Health Ethics” (only in Spanish) is aimed at public health authorities and professionals in the Americas. See also the virtual launch event in Spanish.

Virtual seminars

Ethical preparedness for research in emergencies (June 12, 2026)

Virtual seminar series on topics related to clinical trials

  1. Ethical preparedness for research in emergencies  (June 12, 2026)
  2. Adaptive and platform trials (May 6, 2026)
  3. PAHO Clinical Trial Accelerator (April 9, 2026)
  4. Ethics of human challenge studies (March 2, 2026)
  5. Artificial intelligence and ethics review of research: challenges and opportunities (Dec. 2, 2025)
  6. Rethinking the concept of vulnerability in research (Nov. 7, 2025)
  7. Clinical trials on advanced therapies (Oct. 21, 2025)
  8. Regional template for clinical trial agreement (Aug. 26, 2025)
  9. Ethical inclusion of pregnant participants in clinical trials (Aug. 13, 2025)
  10. Pre-approved protocols for clinical trials: Importance and pending challenges (June 18, 2025)
  11. Template for clinical trial contract and insurance policy: regional proposal (June 4, 2025)
  12. How to promote more and better clinical trials in Latin America and the Caribbean? (May 6, 2025)
  13. New guideline for Good Clinical Practice: E6(R3) (March 18, 2025)
  14. Why and how to promote collaboration in health research? (Feb 27, 2025)
  15. Research contracts and insurance policies for clinical trials: Regional challenges (Dec. 05, 2024)
  16. Research integrity and responsible conduct of research (Nov. 14, 2024)
  17. Clinical trial registration and the International Clinical Trials Registry Platform (ICTRP) (Oct. 9, 2024)
  18. Challenges of adaptive trials (Sep. 25, 2024)
  19. The U.S. single IRB policy: challenges and lessons (Aug. 30, 2024)
  20. Data Monitoring Committees (DMCs) and the role of ethics (Jul. 17, 2024) 
  21. Animal research and the role of committees for the care and use of animals (Jun. 12, 2024) 
     
    Other virtual seminars

    -Tool for the accreditation of research ethics committees (Jan. 31, 2024) 
    -What are the regulatory tasks in the oversight of clinical trials? (Nov. 21, 2023) 

    Virtual regional bilingual workshop: Material Transfer Agreements and Data Transfer Agreements

    -Material and data transfer agreements: basic notions (Oct. 10, 2023) 
    -Material and data transfer agreements in practice (Oct.17, 2023) 
    -Roles, responsibilities, and challenges when using material and data transfer -agreements (Oct. 24, 2023)
    -Regulations of material and data transfer agreements (Oct. 31, 2023)
     

Documents

Communication Materials

Mandates and Strategies

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Events