Tuberculosis (TB) continues to be one of the leading causes of disease and death from infectious disease in the Region of the Americas, particularly among people living with HIV. In 2024, it was estimated that around 350,000 people fell ill with TB and approximately 30,000 died from this cause in the region. Of these deaths, about 29% were associated with TB/HIV co-infection, reflecting the persistent vulnerability of people with HIV to TB and the urgent need to strengthen integrated, timely and people-centred interventions.
TB prevention is one of the most cost-effective interventions to reduce disease and mortality among people living with HIV. Despite international recommendations and strong evidence on the efficacy of tuberculosis preventive treatment (TPT), its implementation remains uneven in the countries of the Region of the Americas, with significant gaps in coverage and access for populations most at risk.
The availability of shorter, safer and more effective schemes, coupled with the simplification of eligibility and tracking algorithms, has created an unprecedented opportunity to expand access to TPT. The expansion of these interventions is critical to advancing regional and global targets to reduce TB incidence and mortality, especially in people with HIV, who are at significantly higher risk of developing TB disease.
However, programs face challenges related to identifying eligible individuals, integrating services, availability of medications, adherence to treatment, and outcome monitoring.
To review current WHO recommendations on the preventive treatment of tuberculosis (TPT) in people with HIV, by presenting the latest evidence on abbreviated TPT regimens, including 3HP, as well as to share experiences of programmatic expansion and implementation of TPT in different contexts of the Region of the Americas, identifying challenges, lessons learned and opportunities to expand their coverage and impact
TB/HIV Webinar Series: Diagnostic innovations for the early detection of tuberculosis in people with HIV
General objective
To review current WHO recommendations on the preventive treatment of tuberculosis (TPT) in people with HIV, by presenting the latest evidence on abbreviated TPT regimens, including 3HP, as well as to share experiences of programmatic expansion and implementation of TPT in different contexts of the Region of the Americas, identifying challenges, lessons learned and opportunities to expand their coverage and impact.
Target audience
- Responsible for national TB and HIV programmes.
- Technical teams of ministries of health.
- Technical experts linked to TB/HIV management.
- Representatives of civil society and community organizations involved in the response to TB and HIV co-infection.
- International cooperation agencies and strategic partners.
Expected results
- Promoting TB/HIV integration into national programmes.
- Visualize common barriers to LAM and TPT implementation.
- Disseminate regional success stories.
Methodology
The series will kick off with two regional webinars that include:
- Technical presentations by experts.
- Panel discussions.
- Exchange of national experiences.
- Q&A sessions.
Date: July 1, 2026.
Time: 10:00 a.m. – 12:00 p.m. Washington, D.C. time (EST)
Modality: Virtual
Simultaneous English-Spanish translation
Zoom Platform
Agenda
10:00
Opening remarks
Omar Sued, HIV Treatment Counselor. HT Unit. OPS, WDC
10:10
Regional situation TPT implementation.
Pedro Avedillo, Advisor on TB Prevention, Control and Elimination. HT Unit in OPS, WDC
10:20
Update WHO recommendations on TPT in people with HIV
Belkys Marcelino, International PAHO Consultant VIH., Unidad HT. OPS, WDC
10:30
Evidence on 3HP TPT in people with HIV.
Richard Chaisson, Johns Hopkins School of Medicine, USA
10:50
Panel: TPT Expansion Experiences in the Region
Increasing Access to TPT in Complex Contexts: The Experience of Haiti
3HP Programmatic Implementation in Honduras: Lessons Learned
Implementation of TPT at the first level of care: experience from Peru
Pedro Avedillo and Omar Sued (Moderation)
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11:30
Questions & Answers
Antonio Camiro, OPS
Belkys Marcelino, OPS
12:00
Closing. Next steps
Pedro Avedillo and Omar Sued
