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Bioethics

Bioethics is the discipline that examines the ethical issues arising in different areas of health, including public health, health care, and health research. Its purpose is to guide decision-making through ethical principles and criteria that protect the dignity, rights, and well-being of individuals and communities.
In the Region of the Americas, PAHO promotes the integration of bioethics into health policies, programs, and actions to strengthen fairer, more responsible, and socially accountable health systems

  • Bioethics is a cross-cutting pillar of public health, health care, and health research.
  • Bioethics examines what ought to be done in health-related situations, beyond what is legally required.
  • It contributes to the protection of individuals in health care and knowledge generation.
  • It provides ethical frameworks for public health decision-making, particularly in contexts of scarcity and resource prioritization.
  • It helps anticipate and address dilemmas linked to new technologies, health emergencies, and complex decisions.
  • Integrating bioethics strengthens transparency, accountability, and public trust in health decisions.

Through its Regional Bioethics Program, PAHO supports Member States in integrating ethics into all health-related activities. The Program promotes a demand-driven, translational bioethics approach, with a focus on public health ethics and research ethics.

Research ethics is the set of principles, norms, and values that guide the conduct of those who carry out research, with the aim of ensuring respect for individuals, scientific integrity, and social responsibility. Public health ethics is the branch of ethics that guides decisions, policies, and actions aimed at protecting and improving the health of populations, balancing collective well-being with individual rights. Both are complementary: ethical research generates reliable evidence, while public health ethics guides how to use that evidence to improve population health in a fair way.

PAHO’s actions include the development of technical guidance, the strengthening of institutional capacities, the promotion of regional networks, and support for ethical deliberation processes that help ensure that research is always ethical and that health decision-making has a positive impact on populations.

Videos on research ethics

When does health research need ethics review?  

What do Research Ethics Committees review?

Courses
Curso Etica de la Salud  Publica
 REGIONAL COURSE: “Ética de la salud pública

Developed by the Regional Program on Bioethics and the PAHO Virtual Campus for Public Health (VCPH), this free, self-paced course on “Public Health Ethics” (only in Spanish) is aimed at public health authorities and professionals in the Americas. See also the virtual launch event in Spanish.

Virtual seminars

Adaptive and platform trials (May 6, 2026)

Virtual seminar series on topics related to clinical trials

  1. Adaptive and platform trials (May 6, 2026)
  2. PAHO Clinical Trial Accelerator (April 9, 2026)
  3. Ethics of human challenge studies (March 2, 2026)
  4. Artificial intelligence and ethics review of research: challenges and opportunities (Dec. 2, 2025)
  5. Rethinking the concept of vulnerability in research (Nov. 7, 2025)
  6. Clinical trials on advanced therapies (Oct. 21, 2025)
  7. Regional template for clinical trial agreement (Aug. 26, 2025)
  8. Ethical inclusion of pregnant participants in clinical trials (Aug. 13, 2025)
  9. Pre-approved protocols for clinical trials: Importance and pending challenges (June 18, 2025)
  10. Template for clinical trial contract and insurance policy: regional proposal (June 4, 2025)
  11. How to promote more and better clinical trials in Latin America and the Caribbean? (May 6, 2025)
  12. New guideline for Good Clinical Practice: E6(R3) (March 18, 2025)
  13. Why and how to promote collaboration in health research? (Feb 27, 2025)
  14. Research contracts and insurance policies for clinical trials: Regional challenges (Dec. 05, 2024)
  15. Research integrity and responsible conduct of research (Nov. 14, 2024)
  16. Clinical trial registration and the International Clinical Trials Registry Platform (ICTRP) (Oct. 9, 2024)
  17. Challenges of adaptive trials (Sep. 25, 2024)
  18. The U.S. single IRB policy: challenges and lessons (Aug. 30, 2024)
  19. Data Monitoring Committees (DMCs) and the role of ethics (Jul. 17, 2024) 
  20. Animal research and the role of committees for the care and use of animals (Jun. 12, 2024) 
     
    Other virtual seminars

    -Tool for the accreditation of research ethics committees (Jan. 31, 2024) 
    -What are the regulatory tasks in the oversight of clinical trials? (Nov. 21, 2023) 

    Virtual regional bilingual workshop: Material Transfer Agreements and Data Transfer Agreements

    -Material and data transfer agreements: basic notions (Oct. 10, 2023) 
    -Material and data transfer agreements in practice (Oct.17, 2023) 
    -Roles, responsibilities, and challenges when using material and data transfer -agreements (Oct. 24, 2023)
    -Regulations of material and data transfer agreements (Oct. 31, 2023)
     

Documents

Events